TESA 10mg
Tesamorelin is a synthetic analog of Growth Hormone Releasing Hormone (GHRH).
Instead of injecting growth hormone directly, Tesamorelin stimulates your own pituitary to produce growth hormone in a physiologic pattern.
That distinction matters.
Reduces visceral fat
Improves waist circumference. Tracking waist size with a tape measure is a practical way to estimate how much visceral fat a person has and monitor changes during peptide therapy.
What Tesamorelin Does:
Increases endogenous growth hormone
Reduces visceral adipose tissue (VAT)
Improves waist circumference
Supports IGF-1 balance
May improve liver fat markers
Tesamorelin has been studied extensively in HIV-associated lipodystrophy, where it significantly reduced visceral fat without the same degree of subcutaneous fat loss.
In functional medicine and longevity-focused care, we use it strategically in patients with:
High visceral fat on imaging or InBody
Central adiposity resistant to diet and exercise
Low IGF-1 with metabolic dysfunction
Early fatty liver patterns
Why It’s Different from GLP-1s
GLP-1 medications reduce appetite and slow gastric emptying.
Tesamorelin works upstream by improving growth hormone signaling; which influences:
Fat partitioning
Lipolysis
Muscle preservation and supports the ability to build muscle and build muscle mass
Metabolic flexibility
This makes it especially valuable for patients who:
Have lost muscle on GLP-1s (Tesamorelin not only helps preserve muscle but also supports muscle repair)
Plateaued with weight loss
Carry disproportionate abdominal fat

